Researchers in the Department of Neurology at the University of Medicine and Dentistry of New Jersey have determined that some members of the Whipple family suffer from a disease known as Machado-Joseph Disease (MJD). MJD is also known as Spinocerebellar Ataxia 3 (SCA3), so named because it was the third of many such ataxias to be identified. “Ataxia” is a general term referring to lack of muscle control.
Characteristics:
MJD is characterized by clumsiness and weakness in the arms and legs, spasticity (continuous, uncontrollable muscle contractions), a staggering lurching gait (easily mistaken for drunkenness), difficulty with speech and swallowing, involuntary eye movements, double vision, and frequent urination. Some patients have ystonia (sustained muscle contractions that cause twisting of the body and limbs, repetitive movements, abnormal posture, and/or rigidity) or symptoms similar to those of Parkinson’s disease. Others have twitching of the face or tongue, or distinct bulging eyes. Almost all MJD patients experience vision problems, including double vision (diplopia) or blurred vision, loss of ability to distinguish color and/or contrast, and inability to control eye movements. (more…)